Unraveling the binding characteristics of small ligands to telomeric DNA by pressure modulation
Abstract Recently, non-canonical DNA structures, such as G-quadruplexes (GQs), were found to be highly pressure sensitive, suggesting that pressure modulation studies can provide additional mechanistic details of such biomolecular systems. Using FRET and CD spectroscopy as well as binding equilibriu...
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Main Authors: | Rosario Oliva, Sanjib Mukherjee, Roland Winter |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/94c9a90a87ed4256a5459e738bc7c9de |
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