Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

Microbial production of isoprene from renewable feedstock is a promising alternative to petroleum-based processes. Here, the authors show that isoprene production in the yeast Saccharomyces cerevisiaecan be improved by dual metabolic engineering of cytoplasmic and mitochondrial acetyl-CoA utilizatio...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiaomei Lv, Fan Wang, Pingping Zhou, Lidan Ye, Wenping Xie, Haoming Xu, Hongwei Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/94d43cdd94ac45db910740a41def94e5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:94d43cdd94ac45db910740a41def94e5
record_format	dspace
spelling	oai:doaj.org-article:94d43cdd94ac45db910740a41def94e52021-12-02T15:35:41ZDual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae10.1038/ncomms128512041-1723https://doaj.org/article/94d43cdd94ac45db910740a41def94e52016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12851https://doaj.org/toc/2041-1723Microbial production of isoprene from renewable feedstock is a promising alternative to petroleum-based processes. Here, the authors show that isoprene production in the yeast Saccharomyces cerevisiaecan be improved by dual metabolic engineering of cytoplasmic and mitochondrial acetyl-CoA utilization.Xiaomei LvFan WangPingping ZhouLidan YeWenping XieHaoming XuHongwei YuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaomei Lv Fan Wang Pingping Zhou Lidan Ye Wenping Xie Haoming Xu Hongwei Yu Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
description	Microbial production of isoprene from renewable feedstock is a promising alternative to petroleum-based processes. Here, the authors show that isoprene production in the yeast Saccharomyces cerevisiaecan be improved by dual metabolic engineering of cytoplasmic and mitochondrial acetyl-CoA utilization.
format	article
author	Xiaomei Lv Fan Wang Pingping Zhou Lidan Ye Wenping Xie Haoming Xu Hongwei Yu
author_facet	Xiaomei Lv Fan Wang Pingping Zhou Lidan Ye Wenping Xie Haoming Xu Hongwei Yu
author_sort	Xiaomei Lv
title	Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
title_short	Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
title_full	Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
title_fullStr	Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
title_full_unstemmed	Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae
title_sort	dual regulation of cytoplasmic and mitochondrial acetyl-coa utilization for improved isoprene production in saccharomyces cerevisiae
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/94d43cdd94ac45db910740a41def94e5
work_keys_str_mv	AT xiaomeilv dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT fanwang dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT pingpingzhou dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT lidanye dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT wenpingxie dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT haomingxu dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae AT hongweiyu dualregulationofcytoplasmicandmitochondrialacetylcoautilizationforimprovedisopreneproductioninsaccharomycescerevisiae
_version_	1718386489782435840

Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

Ejemplares similares