Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

Influenza A virus forms cytosolic inclusions containing viral ribonucleoproteins. Here, the authors show that viral inclusions form juxtaposed the endoplasmic reticulum and have liquid properties, likely constituting sites of assembly of epidemic and pandemic influenza genomes.

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Autores principales: Marta Alenquer, Sílvia Vale-Costa, Temitope Akhigbe Etibor, Filipe Ferreira, Ana Laura Sousa, Maria João Amorim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/94d834963d7a4427afe59405bbcf676a
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spelling oai:doaj.org-article:94d834963d7a4427afe59405bbcf676a2021-12-02T16:57:34ZInfluenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites10.1038/s41467-019-09549-42041-1723https://doaj.org/article/94d834963d7a4427afe59405bbcf676a2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09549-4https://doaj.org/toc/2041-1723Influenza A virus forms cytosolic inclusions containing viral ribonucleoproteins. Here, the authors show that viral inclusions form juxtaposed the endoplasmic reticulum and have liquid properties, likely constituting sites of assembly of epidemic and pandemic influenza genomes.Marta AlenquerSílvia Vale-CostaTemitope Akhigbe EtiborFilipe FerreiraAna Laura SousaMaria João AmorimNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marta Alenquer
Sílvia Vale-Costa
Temitope Akhigbe Etibor
Filipe Ferreira
Ana Laura Sousa
Maria João Amorim
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
description Influenza A virus forms cytosolic inclusions containing viral ribonucleoproteins. Here, the authors show that viral inclusions form juxtaposed the endoplasmic reticulum and have liquid properties, likely constituting sites of assembly of epidemic and pandemic influenza genomes.
format article
author Marta Alenquer
Sílvia Vale-Costa
Temitope Akhigbe Etibor
Filipe Ferreira
Ana Laura Sousa
Maria João Amorim
author_facet Marta Alenquer
Sílvia Vale-Costa
Temitope Akhigbe Etibor
Filipe Ferreira
Ana Laura Sousa
Maria João Amorim
author_sort Marta Alenquer
title Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
title_short Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
title_full Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
title_fullStr Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
title_full_unstemmed Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
title_sort influenza a virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/94d834963d7a4427afe59405bbcf676a
work_keys_str_mv AT martaalenquer influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
AT silviavalecosta influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
AT temitopeakhigbeetibor influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
AT filipeferreira influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
AT analaurasousa influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
AT mariajoaoamorim influenzaavirusribonucleoproteinsformliquidorganellesatendoplasmicreticulumexitsites
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