U1 snRNP regulates cancer cell migration and invasion in vitro

U1 snRNP regulates cancer cell migration and invasion in vitro

U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.

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Bibliographic Details
Main Authors: Jung-Min Oh, Christopher C. Venters, Chao Di, Anna Maria Pinto, Lili Wan, Ihab Younis, Zhiqiang Cai, Chie Arai, Byung Ran So, Jingqi Duan, Gideon Dreyfuss
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160
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Summary:U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.

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