U1 snRNP regulates cancer cell migration and invasion in vitro

U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.

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Autores principales: Jung-Min Oh, Christopher C. Venters, Chao Di, Anna Maria Pinto, Lili Wan, Ihab Younis, Zhiqiang Cai, Chie Arai, Byung Ran So, Jingqi Duan, Gideon Dreyfuss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160
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spelling oai:doaj.org-article:94e6334d86c641beb8ea3c082c7fc1602021-12-02T16:49:14ZU1 snRNP regulates cancer cell migration and invasion in vitro10.1038/s41467-019-13993-72041-1723https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc1602020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13993-7https://doaj.org/toc/2041-1723U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.Jung-Min OhChristopher C. VentersChao DiAnna Maria PintoLili WanIhab YounisZhiqiang CaiChie AraiByung Ran SoJingqi DuanGideon DreyfussNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jung-Min Oh
Christopher C. Venters
Chao Di
Anna Maria Pinto
Lili Wan
Ihab Younis
Zhiqiang Cai
Chie Arai
Byung Ran So
Jingqi Duan
Gideon Dreyfuss
U1 snRNP regulates cancer cell migration and invasion in vitro
description U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.
format article
author Jung-Min Oh
Christopher C. Venters
Chao Di
Anna Maria Pinto
Lili Wan
Ihab Younis
Zhiqiang Cai
Chie Arai
Byung Ran So
Jingqi Duan
Gideon Dreyfuss
author_facet Jung-Min Oh
Christopher C. Venters
Chao Di
Anna Maria Pinto
Lili Wan
Ihab Younis
Zhiqiang Cai
Chie Arai
Byung Ran So
Jingqi Duan
Gideon Dreyfuss
author_sort Jung-Min Oh
title U1 snRNP regulates cancer cell migration and invasion in vitro
title_short U1 snRNP regulates cancer cell migration and invasion in vitro
title_full U1 snRNP regulates cancer cell migration and invasion in vitro
title_fullStr U1 snRNP regulates cancer cell migration and invasion in vitro
title_full_unstemmed U1 snRNP regulates cancer cell migration and invasion in vitro
title_sort u1 snrnp regulates cancer cell migration and invasion in vitro
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160
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