U1 snRNP regulates cancer cell migration and invasion in vitro
U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.
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Nature Portfolio
2020
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oai:doaj.org-article:94e6334d86c641beb8ea3c082c7fc1602021-12-02T16:49:14ZU1 snRNP regulates cancer cell migration and invasion in vitro10.1038/s41467-019-13993-72041-1723https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc1602020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13993-7https://doaj.org/toc/2041-1723U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.Jung-Min OhChristopher C. VentersChao DiAnna Maria PintoLili WanIhab YounisZhiqiang CaiChie AraiByung Ran SoJingqi DuanGideon DreyfussNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020) |
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Science Q Jung-Min Oh Christopher C. Venters Chao Di Anna Maria Pinto Lili Wan Ihab Younis Zhiqiang Cai Chie Arai Byung Ran So Jingqi Duan Gideon Dreyfuss U1 snRNP regulates cancer cell migration and invasion in vitro |
description |
U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling. |
format |
article |
author |
Jung-Min Oh Christopher C. Venters Chao Di Anna Maria Pinto Lili Wan Ihab Younis Zhiqiang Cai Chie Arai Byung Ran So Jingqi Duan Gideon Dreyfuss |
author_facet |
Jung-Min Oh Christopher C. Venters Chao Di Anna Maria Pinto Lili Wan Ihab Younis Zhiqiang Cai Chie Arai Byung Ran So Jingqi Duan Gideon Dreyfuss |
author_sort |
Jung-Min Oh |
title |
U1 snRNP regulates cancer cell migration and invasion in vitro |
title_short |
U1 snRNP regulates cancer cell migration and invasion in vitro |
title_full |
U1 snRNP regulates cancer cell migration and invasion in vitro |
title_fullStr |
U1 snRNP regulates cancer cell migration and invasion in vitro |
title_full_unstemmed |
U1 snRNP regulates cancer cell migration and invasion in vitro |
title_sort |
u1 snrnp regulates cancer cell migration and invasion in vitro |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160 |
work_keys_str_mv |
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