U1 snRNP regulates cancer cell migration and invasion in vitro
U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptome profiling.
Enregistré dans:
Auteurs principaux: | Jung-Min Oh, Christopher C. Venters, Chao Di, Anna Maria Pinto, Lili Wan, Ihab Younis, Zhiqiang Cai, Chie Arai, Byung Ran So, Jingqi Duan, Gideon Dreyfuss |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation
par: Klára Klimešová, et autres
Publié: (2021) -
Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors
par: Constantin Cretu, et autres
Publié: (2021) -
Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA
par: Eric J. Montemayor, et autres
Publié: (2018) -
Interaction of 7SK with the Smn complex modulates snRNP production
par: Changhe Ji, et autres
Publié: (2021) -
CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing
par: Xueni Li, et autres
Publié: (2017)