High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

Abstract Conventional chemotherapeutic agents are nonselective, often resulting in severe side effects and the development of resistance. Therefore, new molecular-targeted therapies are urgently needed to be integrated into existing treatment regimens. Here, we performed a high-throughput compound s...

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Autores principales: Katja Tuomainen, Aini Hyytiäinen, Ahmed Al-Samadi, Philipp Ianevski, Aleksandr Ianevski, Swapnil Potdar, Laura Turunen, Jani Saarela, Sergey Kuznetsov, Wafa Wahbi, Maija Risteli, Antti Mäkitie, Outi Monni, Tuula Salo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/94f7ab850a6441f089e9e315a0b84667
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