Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®

Martin Haensig, Friedrich Wilhelm Mohr, Ardawan Julian RastanDepartment of Cardiac Surgery, Heart Center, University of Leipzig, Leipzig, GermanyAbstract: Treatment of a number of congenital heart defects often necessitates staged surgical intervention. In addition, substantial improvements in posto...

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Autores principales: Martin Haensig, Friedrich Wilhelm Mohr, Ardawan Julian Rastan
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Lenguaje:EN
Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:94fbc74a77e24cab879db8079996b3862021-12-02T07:05:20ZBioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®1179-1470https://doaj.org/article/94fbc74a77e24cab879db8079996b3862011-01-01T00:00:00Zhttp://www.dovepress.com/bioresorbable-adhesion-barrier-for-reducing-the-severity-of-postoperat-a6050https://doaj.org/toc/1179-1470Martin Haensig, Friedrich Wilhelm Mohr, Ardawan Julian RastanDepartment of Cardiac Surgery, Heart Center, University of Leipzig, Leipzig, GermanyAbstract: Treatment of a number of congenital heart defects often necessitates staged surgical intervention. In addition, substantial improvements in postoperative cardiac care and more liberal use of biological valve substitutes have resulted in many adult patients surviving to become potential candidates for reoperations to repair or replace valves or to undergo additional revascularization procedures. In all these scenarios, surgeons are confronted with cardiac adhesions, leading to an increased surgical risk. Thus, bioresorbable adhesion barriers had become of increasing interest because they are easy to use, and safe and effective. This review focuses on the mechanisms by which REPEL-CV® prevents adhesive processes, as well as the development, design, and materials used, and also summarizes efficacy studies, clinical data, safety, and current role in therapy.Keywords: adhesion prevention, bioresorbable copolymer, cardiac reoperation Martin HaensigFriedrich Wilhelm MohrArdawan Julian RastanDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2011, Iss default, Pp 17-25 (2011)
institution DOAJ
collection DOAJ
language EN
topic Medical technology
R855-855.5
spellingShingle Medical technology
R855-855.5
Martin Haensig
Friedrich Wilhelm Mohr
Ardawan Julian Rastan
Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
description Martin Haensig, Friedrich Wilhelm Mohr, Ardawan Julian RastanDepartment of Cardiac Surgery, Heart Center, University of Leipzig, Leipzig, GermanyAbstract: Treatment of a number of congenital heart defects often necessitates staged surgical intervention. In addition, substantial improvements in postoperative cardiac care and more liberal use of biological valve substitutes have resulted in many adult patients surviving to become potential candidates for reoperations to repair or replace valves or to undergo additional revascularization procedures. In all these scenarios, surgeons are confronted with cardiac adhesions, leading to an increased surgical risk. Thus, bioresorbable adhesion barriers had become of increasing interest because they are easy to use, and safe and effective. This review focuses on the mechanisms by which REPEL-CV® prevents adhesive processes, as well as the development, design, and materials used, and also summarizes efficacy studies, clinical data, safety, and current role in therapy.Keywords: adhesion prevention, bioresorbable copolymer, cardiac reoperation
format article
author Martin Haensig
Friedrich Wilhelm Mohr
Ardawan Julian Rastan
author_facet Martin Haensig
Friedrich Wilhelm Mohr
Ardawan Julian Rastan
author_sort Martin Haensig
title Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
title_short Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
title_full Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
title_fullStr Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
title_full_unstemmed Bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: Focus on REPEL-CV®
title_sort bioresorbable adhesion barrier for reducing the severity of postoperative cardiac adhesions: focus on repel-cv®
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/94fbc74a77e24cab879db8079996b386
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AT ardawanjulianrastan bioresorbableadhesionbarrierforreducingtheseverityofpostoperativecardiacadhesionsfocusonrepelcvampreg
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