Identifying the lungs as a susceptible site for allele-specific regulatory changes associated with type 1 diabetes risk
Ho, Nyaga et al. develop a machine learning approach for ranking tissue-specific gene regulatory affects, used here for type 1 diabetes SNPs. They identify the lung as a site where these regulatory impacts can be most impactful, which may contribute to understanding the link between respiratory issu...
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Autores principales: | Daniel Ho, Denis M. Nyaga, William Schierding, Richard Saffery, Jo K. Perry, John A. Taylor, Mark H. Vickers, Andreas W. Kempa-Liehr, Justin M. O’Sullivan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9509bda596664eab9816f6a97f9db45f |
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