Mesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies.

Mesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies.

<h4>Background</h4>Mounting clinical and experimental evidence suggests that the shift of carcinomas towards a mesenchymal phenotype is a common paradigm for both resistance to therapy and tumor recurrence. However, the mesenchymalization of carcinomas has not yet entered clinical practi...

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Autores principales: Cristina Marchini, Maura Montani, Georgia Konstantinidou, Rita Orrù, Silvia Mannucci, Giorgio Ramadori, Federico Gabrielli, Anna Baruzzi, Giorgio Berton, Flavia Merigo, Stefania Fin, Manuela Iezzi, Brigitte Bisaro, Andrea Sbarbati, Massimo Zerani, Mirco Galiè, Augusto Amici
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/950ce2c2c1144253a2591cb5960aa677
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