Practicable assessment of cochlear size and shape from clinical CT images

Abstract There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choi...

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Autores principales:	Andrew H. Gee, Yufeng Zhao, Graham M. Treece, Manohar L. Bance
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/950cf7577b4448ccb6e626d7f3aa60cc
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spelling	oai:doaj.org-article:950cf7577b4448ccb6e626d7f3aa60cc2021-12-02T14:11:29ZPracticable assessment of cochlear size and shape from clinical CT images10.1038/s41598-021-83059-62045-2322https://doaj.org/article/950cf7577b4448ccb6e626d7f3aa60cc2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83059-6https://doaj.org/toc/2045-2322Abstract There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8–17% of the gold-standard sample range for non-planarity, cochlear size and duct length.Andrew H. GeeYufeng ZhaoGraham M. TreeceManohar L. BanceNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Andrew H. Gee Yufeng Zhao Graham M. Treece Manohar L. Bance Practicable assessment of cochlear size and shape from clinical CT images
description	Abstract There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8–17% of the gold-standard sample range for non-planarity, cochlear size and duct length.
format	article
author	Andrew H. Gee Yufeng Zhao Graham M. Treece Manohar L. Bance
author_facet	Andrew H. Gee Yufeng Zhao Graham M. Treece Manohar L. Bance
author_sort	Andrew H. Gee
title	Practicable assessment of cochlear size and shape from clinical CT images
title_short	Practicable assessment of cochlear size and shape from clinical CT images
title_full	Practicable assessment of cochlear size and shape from clinical CT images
title_fullStr	Practicable assessment of cochlear size and shape from clinical CT images
title_full_unstemmed	Practicable assessment of cochlear size and shape from clinical CT images
title_sort	practicable assessment of cochlear size and shape from clinical ct images
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/950cf7577b4448ccb6e626d7f3aa60cc
work_keys_str_mv	AT andrewhgee practicableassessmentofcochlearsizeandshapefromclinicalctimages AT yufengzhao practicableassessmentofcochlearsizeandshapefromclinicalctimages AT grahammtreece practicableassessmentofcochlearsizeandshapefromclinicalctimages AT manoharlbance practicableassessmentofcochlearsizeandshapefromclinicalctimages
_version_	1718391857901207552

Practicable assessment of cochlear size and shape from clinical CT images

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