Pangenome Analytics Reveal Two-Component Systems as Conserved Targets in ESKAPEE Pathogens

Pangenome Analytics Reveal Two-Component Systems as Conserved Targets in ESKAPEE Pathogens

ABSTRACT The two-component system (TCS) helps bacteria sense and respond to environmental stimuli through histidine kinases and response regulators. TCSs are the largest family of multistep signal transduction processes, and they are involved in many important cellular processes such as antibiotic r...

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Autores principales: Akanksha Rajput, Yara Seif, Kumari Sonal Choudhary, Christopher Dalldorf, Saugat Poudel, Jonathan M. Monk, Bernhard O. Palsson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
ESKAPEE pathogens
pangenomic analysis
two-component systems
antibiotic resistance
genomic architecture
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/950ea538f1be458d9d0ab5b3eba61436
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