Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Abstract While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity. We recently generated a Plasmodium berghei (PbNK65) parasite that lacks a secreted factor, the...

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Autores principales: Claudia Demarta-Gatsi, Roger Peronet, Leanna Smith, Sabine Thiberge, Robert Ménard, Salaheddine Mécheri
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/95149685224d4ca18f02fb78631c3175
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