The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation
Aim: The connection between revascularization for coronary artery disease (CAD) and the incidence of recurrent events of atrial fibrillation (AF) after ablation is unclear. This study aimed to explore the relationship between coronary revascularization and AF recurrence in patients who underwent rad...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/9516088c804f4ebf8ef56db5f39787f3 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:9516088c804f4ebf8ef56db5f39787f3 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:9516088c804f4ebf8ef56db5f39787f32021-11-19T05:20:29ZThe Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation2297-055X10.3389/fcvm.2021.756552https://doaj.org/article/9516088c804f4ebf8ef56db5f39787f32021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.756552/fullhttps://doaj.org/toc/2297-055XAim: The connection between revascularization for coronary artery disease (CAD) and the incidence of recurrent events of atrial fibrillation (AF) after ablation is unclear. This study aimed to explore the relationship between coronary revascularization and AF recurrence in patients who underwent radiofrequency catheter ablation (RFCA).Methods: Four hundred and nineteen patients who underwent performed coronary angiography at the same time as RFCA were enrolled in this study. Obstructive CAD was defined as at least one coronary artery vessel stenosis of ≥75% and percutaneous coronary intervention (PCI) was recommended. Non-obstructive CAD was defined as coronary artery vessel stenosis of <75%. The endpoint was freedom from recurrence from AF after RFCA during the 24-month follow-up.Results: In total, 102, 95, and 212 patients were undergone coronary angiography and diagnosed as having obstructive CAD, Non-obstructive CAD, and Non-CAD, respectively. During the 24-month follow-up period, patients without obstructive CAD were significantly more likely to achieve freedom from AF than patients with obstructive CAD (hazard ratio [HR]: 1.72; 95% confidence interval [CI]: 1.23–2.41; P = 0.001). The recurrence rate of AF was significantly lower in patients who underwent PCI than in those who did not (HR: 0.45; 95% CI: 0.25–0.80; P = 0.007). The multivariate regression analysis showed that the other predictors of AF recurrence for obstructive CAD were multivessel stenosis (HR: 1.92; 95% CI: 1.04–3.54; P = 0.036) and left atrial diameter (HR: 2.56; 95% CI: 1.31–5.00; P = 0.006).Conclusions: This study suggests that obstructive CAD is associated with a higher rate of AF recurrence. Additionally, For patients with CAD, coronary revascularization is related to a lower recurrence rate of AF after RFCA.Xiaowei ChenJiangtao ZhaoKui ZhuFen QinHengdao LiuHailong TaoFrontiers Media S.A.articleatrial fibrillationradiofrequency catheter ablationcoronary artery diseasepercutaneous coronary interventionrecurrenceDiseases of the circulatory (Cardiovascular) systemRC666-701ENFrontiers in Cardiovascular Medicine, Vol 8 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
atrial fibrillation radiofrequency catheter ablation coronary artery disease percutaneous coronary intervention recurrence Diseases of the circulatory (Cardiovascular) system RC666-701 |
| spellingShingle |
atrial fibrillation radiofrequency catheter ablation coronary artery disease percutaneous coronary intervention recurrence Diseases of the circulatory (Cardiovascular) system RC666-701 Xiaowei Chen Jiangtao Zhao Kui Zhu Fen Qin Hengdao Liu Hailong Tao The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| description |
Aim: The connection between revascularization for coronary artery disease (CAD) and the incidence of recurrent events of atrial fibrillation (AF) after ablation is unclear. This study aimed to explore the relationship between coronary revascularization and AF recurrence in patients who underwent radiofrequency catheter ablation (RFCA).Methods: Four hundred and nineteen patients who underwent performed coronary angiography at the same time as RFCA were enrolled in this study. Obstructive CAD was defined as at least one coronary artery vessel stenosis of ≥75% and percutaneous coronary intervention (PCI) was recommended. Non-obstructive CAD was defined as coronary artery vessel stenosis of <75%. The endpoint was freedom from recurrence from AF after RFCA during the 24-month follow-up.Results: In total, 102, 95, and 212 patients were undergone coronary angiography and diagnosed as having obstructive CAD, Non-obstructive CAD, and Non-CAD, respectively. During the 24-month follow-up period, patients without obstructive CAD were significantly more likely to achieve freedom from AF than patients with obstructive CAD (hazard ratio [HR]: 1.72; 95% confidence interval [CI]: 1.23–2.41; P = 0.001). The recurrence rate of AF was significantly lower in patients who underwent PCI than in those who did not (HR: 0.45; 95% CI: 0.25–0.80; P = 0.007). The multivariate regression analysis showed that the other predictors of AF recurrence for obstructive CAD were multivessel stenosis (HR: 1.92; 95% CI: 1.04–3.54; P = 0.036) and left atrial diameter (HR: 2.56; 95% CI: 1.31–5.00; P = 0.006).Conclusions: This study suggests that obstructive CAD is associated with a higher rate of AF recurrence. Additionally, For patients with CAD, coronary revascularization is related to a lower recurrence rate of AF after RFCA. |
| format |
article |
| author |
Xiaowei Chen Jiangtao Zhao Kui Zhu Fen Qin Hengdao Liu Hailong Tao |
| author_facet |
Xiaowei Chen Jiangtao Zhao Kui Zhu Fen Qin Hengdao Liu Hailong Tao |
| author_sort |
Xiaowei Chen |
| title |
The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| title_short |
The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| title_full |
The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| title_fullStr |
The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| title_full_unstemmed |
The Association Between Recurrence of Atrial Fibrillation and Revascularization in Patients With Coronary Artery Disease After Catheter Ablation |
| title_sort |
association between recurrence of atrial fibrillation and revascularization in patients with coronary artery disease after catheter ablation |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/9516088c804f4ebf8ef56db5f39787f3 |
| work_keys_str_mv |
AT xiaoweichen theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT jiangtaozhao theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT kuizhu theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT fenqin theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT hengdaoliu theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT hailongtao theassociationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT xiaoweichen associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT jiangtaozhao associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT kuizhu associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT fenqin associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT hengdaoliu associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation AT hailongtao associationbetweenrecurrenceofatrialfibrillationandrevascularizationinpatientswithcoronaryarterydiseaseaftercatheterablation |
| _version_ |
1718420387100884992 |