Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A <italic toggle="yes">Streptococcus</italic> Survival in Macrophages

Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A <italic toggle="yes">Streptococcus</italic> Survival in Macrophages

ABSTRACT Group A Streptococcus (GAS, Streptococcus pyogenes) is an ongoing threat to human health as the agent of streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as necrotizing fasciitis and streptococcal toxic shock syndrome. In animal models of infe...

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Bibliographic Details
Main Authors: Benedicte Bastiat-Sempe, John F. Love, Natalie Lomayesva, Michael R. Wessels
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/95193ad71c1e43a19f5f9c7381440917
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