Bacterial Signaling Nucleotides Inhibit Yeast Cell Growth by Impacting Mitochondrial and Other Specifically Eukaryotic Functions

ABSTRACT We have engineered Saccharomyces cerevisiae to inducibly synthesize the prokaryotic signaling nucleotides cyclic di-GMP (cdiGMP), cdiAMP, and ppGpp in order to characterize the range of effects these nucleotides exert on eukaryotic cell function during bacterial pathogenesis. Synthetic gene...

Full description

Saved in:
Bibliographic Details
Main Authors: Andy Hesketh, Marta Vergnano, Chris Wan, Stephen G. Oliver
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://doaj.org/article/95212422ff484c7a9bc617018791b4f8
Tags: Add Tag
No Tags, Be the first to tag this record!