Colonization and genetic diversification processes of Leishmania infantum in the Americas

Philipp Schwabl, Mariana Boité, and colleagues analyze 126 Leishmania infantum genomes to determine how demographic and selective consequences of the parasite’s invasive history have contributed to intricate population genetic heterogeneity across Brazil. Their data suggest a complex interplay of po...

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Autores principales:	Philipp Schwabl, Mariana C. Boité, Giovanni Bussotti, Arne Jacobs, Bjorn Andersson, Otacilio Moreira, Anita L. Freitas-Mesquita, Jose Roberto Meyer-Fernandes, Erich L. Telleria, Yara Traub-Csekö, Slavica Vaselek, Tereza Leštinová, Petr Volf, Fernanda N. Morgado, Renato Porrozzi, Martin Llewellyn, Gerald F. Späth, Elisa Cupolillo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/952a916d063940bf8467bb4f472fdc13
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spelling	oai:doaj.org-article:952a916d063940bf8467bb4f472fdc132021-12-02T13:24:17ZColonization and genetic diversification processes of Leishmania infantum in the Americas10.1038/s42003-021-01658-52399-3642https://doaj.org/article/952a916d063940bf8467bb4f472fdc132021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01658-5https://doaj.org/toc/2399-3642Philipp Schwabl, Mariana Boité, and colleagues analyze 126 Leishmania infantum genomes to determine how demographic and selective consequences of the parasite’s invasive history have contributed to intricate population genetic heterogeneity across Brazil. Their data suggest a complex interplay of population expansion, secondary contact and genetic exchange events underlying diversity patterns at short and long-distance scales. These processes also appear pivotal to the proliferation of a drug resistance-associated multi-gene deletion on chromosome 31.Philipp SchwablMariana C. BoitéGiovanni BussottiArne JacobsBjorn AnderssonOtacilio MoreiraAnita L. Freitas-MesquitaJose Roberto Meyer-FernandesErich L. TelleriaYara Traub-CseköSlavica VaselekTereza LeštinováPetr VolfFernanda N. MorgadoRenato PorrozziMartin LlewellynGerald F. SpäthElisa CupolilloNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Philipp Schwabl Mariana C. Boité Giovanni Bussotti Arne Jacobs Bjorn Andersson Otacilio Moreira Anita L. Freitas-Mesquita Jose Roberto Meyer-Fernandes Erich L. Telleria Yara Traub-Csekö Slavica Vaselek Tereza Leštinová Petr Volf Fernanda N. Morgado Renato Porrozzi Martin Llewellyn Gerald F. Späth Elisa Cupolillo Colonization and genetic diversification processes of Leishmania infantum in the Americas
description	Philipp Schwabl, Mariana Boité, and colleagues analyze 126 Leishmania infantum genomes to determine how demographic and selective consequences of the parasite’s invasive history have contributed to intricate population genetic heterogeneity across Brazil. Their data suggest a complex interplay of population expansion, secondary contact and genetic exchange events underlying diversity patterns at short and long-distance scales. These processes also appear pivotal to the proliferation of a drug resistance-associated multi-gene deletion on chromosome 31.
format	article
author	Philipp Schwabl Mariana C. Boité Giovanni Bussotti Arne Jacobs Bjorn Andersson Otacilio Moreira Anita L. Freitas-Mesquita Jose Roberto Meyer-Fernandes Erich L. Telleria Yara Traub-Csekö Slavica Vaselek Tereza Leštinová Petr Volf Fernanda N. Morgado Renato Porrozzi Martin Llewellyn Gerald F. Späth Elisa Cupolillo
author_facet	Philipp Schwabl Mariana C. Boité Giovanni Bussotti Arne Jacobs Bjorn Andersson Otacilio Moreira Anita L. Freitas-Mesquita Jose Roberto Meyer-Fernandes Erich L. Telleria Yara Traub-Csekö Slavica Vaselek Tereza Leštinová Petr Volf Fernanda N. Morgado Renato Porrozzi Martin Llewellyn Gerald F. Späth Elisa Cupolillo
author_sort	Philipp Schwabl
title	Colonization and genetic diversification processes of Leishmania infantum in the Americas
title_short	Colonization and genetic diversification processes of Leishmania infantum in the Americas
title_full	Colonization and genetic diversification processes of Leishmania infantum in the Americas
title_fullStr	Colonization and genetic diversification processes of Leishmania infantum in the Americas
title_full_unstemmed	Colonization and genetic diversification processes of Leishmania infantum in the Americas
title_sort	colonization and genetic diversification processes of leishmania infantum in the americas
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/952a916d063940bf8467bb4f472fdc13
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Colonization and genetic diversification processes of Leishmania infantum in the Americas

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