Hippo signaling suppresses tumor cell metastasis via a Yki-Src42A positive feedback loop
Abstract Metastasis is an important cause of death from malignant tumors. It is of great significance to explore the molecular mechanism of metastasis for the development of anti-cancer drugs. Here, we find that the Hippo pathway hampers tumor cell metastasis in vivo. Silence of hpo or its downstrea...
Guardado en:
Autores principales: | Yan Ding, Guiping Wang, Meixiao Zhan, Xiaohan Sun, Yanran Deng, Yunhe Zhao, Bin Liu, Qingxin Liu, Shian Wu, Zizhang Zhou |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9549fca3d5f74864b8029b48f1e17014 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
miR-497-5p/SALL4 axis promotes stemness phenotype of choriocarcinoma and forms a feedback loop with DNMT-mediated epigenetic regulation
por: Zheng Peng, et al.
Publicado: (2021) -
CircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop
por: Lin-Jing Gong, et al.
Publicado: (2021) -
SRC-3 Knockout Attenuates Myocardial Injury Induced by Chronic Intermittent Hypoxia in Mice
por: Wanyu Wang, et al.
Publicado: (2021) -
ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway
por: Yun Lin, et al.
Publicado: (2021) -
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
por: Ya Meng, et al.
Publicado: (2021)