Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.

Enteroviruses (EV) have been increasingly identified as the causative agent for unknown etiological encephalitis in many parts of the world, but the long period surveillance for enterovirus-associated encephalitis (EAE) was not reported in China. From 2002-2012 in Zhejiang, Coxsackieviruses A9, B1,...

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Autores principales:	Lei Zhang, Jie Yan, David M Ojcius, Huakun Lv, Ziping Miao, Yin Chen, Yanjun Zhang, Jvying Yan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/954c8a3dc16a435ea0a718136fe25e71
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spelling	oai:doaj.org-article:954c8a3dc16a435ea0a718136fe25e712021-11-18T08:39:45ZNovel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.1932-620310.1371/journal.pone.0085023https://doaj.org/article/954c8a3dc16a435ea0a718136fe25e712013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24386442/?tool=EBIhttps://doaj.org/toc/1932-6203Enteroviruses (EV) have been increasingly identified as the causative agent for unknown etiological encephalitis in many parts of the world, but the long period surveillance for enterovirus-associated encephalitis (EAE) was not reported in China. From 2002-2012 in Zhejiang, Coxsackieviruses A9, B1, B2, B3, B4, B5; and echoviruses 3, 4, 6, 9, 14, 25, 30 were detected from the unknown etiological encephalitis cases, with coxsackievirus B4 been identified here for the first time. From 2002-2004 and 2010-2012, echovirus 30 was found to be the periodically predominant serotype for in the EAE. The molecular typing results showed that all the EV isolates from this study belonged to the human EV B (HEV B) family and were distributed in three clusters.Lei ZhangJie YanDavid M OjciusHuakun LvZiping MiaoYin ChenYanjun ZhangJvying YanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e85023 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lei Zhang Jie Yan David M Ojcius Huakun Lv Ziping Miao Yin Chen Yanjun Zhang Jvying Yan Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
description	Enteroviruses (EV) have been increasingly identified as the causative agent for unknown etiological encephalitis in many parts of the world, but the long period surveillance for enterovirus-associated encephalitis (EAE) was not reported in China. From 2002-2012 in Zhejiang, Coxsackieviruses A9, B1, B2, B3, B4, B5; and echoviruses 3, 4, 6, 9, 14, 25, 30 were detected from the unknown etiological encephalitis cases, with coxsackievirus B4 been identified here for the first time. From 2002-2004 and 2010-2012, echovirus 30 was found to be the periodically predominant serotype for in the EAE. The molecular typing results showed that all the EV isolates from this study belonged to the human EV B (HEV B) family and were distributed in three clusters.
format	article
author	Lei Zhang Jie Yan David M Ojcius Huakun Lv Ziping Miao Yin Chen Yanjun Zhang Jvying Yan
author_facet	Lei Zhang Jie Yan David M Ojcius Huakun Lv Ziping Miao Yin Chen Yanjun Zhang Jvying Yan
author_sort	Lei Zhang
title	Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
title_short	Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
title_full	Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
title_fullStr	Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
title_full_unstemmed	Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.
title_sort	novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern china.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/954c8a3dc16a435ea0a718136fe25e71
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Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China.

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