Structural transitions during the scaffolding-driven assembly of a viral capsid

Viral assembly is a complex process that in tailed bacteriophages involves scaffolding proteins which coordinate assembly of the phage procapsid and are subsequently released during maturation. Here the authors reveal the conformational changes that accompany virion maturation, documenting how the d...

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Autores principales:	Athanasios Ignatiou, Sandrine Brasilès, Mehdi El Sadek Fadel, Jörg Bürger, Thorsten Mielke, Maya Topf, Paulo Tavares, Elena V. Orlova
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9550faea551f487fbc11250461307f8f
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spelling	oai:doaj.org-article:9550faea551f487fbc11250461307f8f2021-12-02T14:39:02ZStructural transitions during the scaffolding-driven assembly of a viral capsid10.1038/s41467-019-12790-62041-1723https://doaj.org/article/9550faea551f487fbc11250461307f8f2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12790-6https://doaj.org/toc/2041-1723Viral assembly is a complex process that in tailed bacteriophages involves scaffolding proteins which coordinate assembly of the phage procapsid and are subsequently released during maturation. Here the authors reveal the conformational changes that accompany virion maturation, documenting how the dissociation of scaffold proteins and DNA packaging processes intersect.Athanasios IgnatiouSandrine BrasilèsMehdi El Sadek FadelJörg BürgerThorsten MielkeMaya TopfPaulo TavaresElena V. OrlovaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Athanasios Ignatiou Sandrine Brasilès Mehdi El Sadek Fadel Jörg Bürger Thorsten Mielke Maya Topf Paulo Tavares Elena V. Orlova Structural transitions during the scaffolding-driven assembly of a viral capsid
description	Viral assembly is a complex process that in tailed bacteriophages involves scaffolding proteins which coordinate assembly of the phage procapsid and are subsequently released during maturation. Here the authors reveal the conformational changes that accompany virion maturation, documenting how the dissociation of scaffold proteins and DNA packaging processes intersect.
format	article
author	Athanasios Ignatiou Sandrine Brasilès Mehdi El Sadek Fadel Jörg Bürger Thorsten Mielke Maya Topf Paulo Tavares Elena V. Orlova
author_facet	Athanasios Ignatiou Sandrine Brasilès Mehdi El Sadek Fadel Jörg Bürger Thorsten Mielke Maya Topf Paulo Tavares Elena V. Orlova
author_sort	Athanasios Ignatiou
title	Structural transitions during the scaffolding-driven assembly of a viral capsid
title_short	Structural transitions during the scaffolding-driven assembly of a viral capsid
title_full	Structural transitions during the scaffolding-driven assembly of a viral capsid
title_fullStr	Structural transitions during the scaffolding-driven assembly of a viral capsid
title_full_unstemmed	Structural transitions during the scaffolding-driven assembly of a viral capsid
title_sort	structural transitions during the scaffolding-driven assembly of a viral capsid
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9550faea551f487fbc11250461307f8f
work_keys_str_mv	AT athanasiosignatiou structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT sandrinebrasiles structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT mehdielsadekfadel structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT jorgburger structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT thorstenmielke structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT mayatopf structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT paulotavares structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid AT elenavorlova structuraltransitionsduringthescaffoldingdrivenassemblyofaviralcapsid
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Structural transitions during the scaffolding-driven assembly of a viral capsid

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