Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance

Type 2 diabetes is associated with chronic inflammation and is characterized by insulin resistance. Here, the authors identify a crucial role for endothelial BMPER function in glucose homeostasis, and BMPER overexpression was shown to alleviate insulin resistance and hyperglycemia in diabetic mice.

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Bibliographic Details
Main Authors: Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Huaizhu Wu, Christie M. Ballantyne, Sean M. Hartig, Liang Xie, Xinchun Pi
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/955957e083474c468a00c6e9258ec4a1
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