Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study

Li Jiang, Scott Eaves, Navpreet Dhillon, Punithawathy Ranjit Ophthalmology Department, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK Purpose: To assess and compare the long-term postoperative outcomes of trabeculectomy (TE), phacotrabeculectomy (PTE), and viscocanalostomy (V...

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Autores principales:	Jiang L, Eaves S, Dhillon N, Ranjit P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	glaucoma trabeculectomy viscocanalostomy post-operative outcomes Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9564f881794d40ae9046e1e74459315f
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spelling	oai:doaj.org-article:9564f881794d40ae9046e1e74459315f2021-12-02T01:54:44ZPostoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study1177-5483https://doaj.org/article/9564f881794d40ae9046e1e74459315f2018-05-01T00:00:00Zhttps://www.dovepress.com/postoperative-outcomes-following-trabeculectomy-and-nonpenetrating-sur-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Li Jiang, Scott Eaves, Navpreet Dhillon, Punithawathy Ranjit Ophthalmology Department, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK Purpose: To assess and compare the long-term postoperative outcomes of trabeculectomy (TE), phacotrabeculectomy (PTE), and viscocanalostomy (VC) and to correlate postoperative intraocular pressure (IOP) with visual outcome.Patients and methods: This retrospective cohort observational study included 520 eyes which underwent TE with mitomycin C (MMC) (n=205), PTE with MMC (n=189), and VC ± combined cataract surgery and MMC (n=126) to control IOP between June 2010 and June 2014 by a single surgeon. Complete success was defined as postoperative IOP <20 mmHg, and qualified success with IOP <20 mmHg with single topical agent. Cases requiring more than one topical agent and/or repeat surgery were considered as failure. Mixed linear regression models were constructed to determine estimated predictive values of demographic data, topical prescriptions, baseline and postoperative IOP, and optical assessment (ie, best-corrected visual acuity and mean deviation) profile.Results: Follow-up ranged from 12 to 66 months (mean 26 months). At last follow-up, 139 (93.9%), 118 (91.5%), and 98 (94.2%) eyes achieved complete success in TE, PTE, and VC groups, respectively (p=0.0007). Failure rates were 2.7%, 3.9%, and 2.9% following TE, PTE, and VC, respectively (p=0.0052). The between-group difference of mean IOP reduction was greater in the short term (p=0.0002). Good postoperative IOP control correlates to optical outcomes reflected by best-corrected visual acuity and mean deviation following TE (β = -4.7577, p=0.0384) and PTE (β = -4.5083, p=0.02741).Conclusion: Significant association was observed between good postoperative IOP control and optical outcome. TE remains the more effective surgical intervention for sustained lowering of IOP. Most complications were transient and self-limiting. Keywords: traveculectomy, viscocanalostomy, intraocular pressure, postoperative outcomeJiang LEaves SDhillon NRanjit PDove Medical Pressarticleglaucomatrabeculectomyviscocanalostomypost-operative outcomesOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 995-1002 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	glaucoma trabeculectomy viscocanalostomy post-operative outcomes Ophthalmology RE1-994
spellingShingle	glaucoma trabeculectomy viscocanalostomy post-operative outcomes Ophthalmology RE1-994 Jiang L Eaves S Dhillon N Ranjit P Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
description	Li Jiang, Scott Eaves, Navpreet Dhillon, Punithawathy Ranjit Ophthalmology Department, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK Purpose: To assess and compare the long-term postoperative outcomes of trabeculectomy (TE), phacotrabeculectomy (PTE), and viscocanalostomy (VC) and to correlate postoperative intraocular pressure (IOP) with visual outcome.Patients and methods: This retrospective cohort observational study included 520 eyes which underwent TE with mitomycin C (MMC) (n=205), PTE with MMC (n=189), and VC ± combined cataract surgery and MMC (n=126) to control IOP between June 2010 and June 2014 by a single surgeon. Complete success was defined as postoperative IOP <20 mmHg, and qualified success with IOP <20 mmHg with single topical agent. Cases requiring more than one topical agent and/or repeat surgery were considered as failure. Mixed linear regression models were constructed to determine estimated predictive values of demographic data, topical prescriptions, baseline and postoperative IOP, and optical assessment (ie, best-corrected visual acuity and mean deviation) profile.Results: Follow-up ranged from 12 to 66 months (mean 26 months). At last follow-up, 139 (93.9%), 118 (91.5%), and 98 (94.2%) eyes achieved complete success in TE, PTE, and VC groups, respectively (p=0.0007). Failure rates were 2.7%, 3.9%, and 2.9% following TE, PTE, and VC, respectively (p=0.0052). The between-group difference of mean IOP reduction was greater in the short term (p=0.0002). Good postoperative IOP control correlates to optical outcomes reflected by best-corrected visual acuity and mean deviation following TE (β = -4.7577, p=0.0384) and PTE (β = -4.5083, p=0.02741).Conclusion: Significant association was observed between good postoperative IOP control and optical outcome. TE remains the more effective surgical intervention for sustained lowering of IOP. Most complications were transient and self-limiting. Keywords: traveculectomy, viscocanalostomy, intraocular pressure, postoperative outcome
format	article
author	Jiang L Eaves S Dhillon N Ranjit P
author_facet	Jiang L Eaves S Dhillon N Ranjit P
author_sort	Jiang L
title	Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
title_short	Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
title_full	Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
title_fullStr	Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
title_full_unstemmed	Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
title_sort	postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/9564f881794d40ae9046e1e74459315f
work_keys_str_mv	AT jiangl postoperativeoutcomesfollowingtrabeculectomyandnonpenetratingsurgicalproceduresa5yearlongitudinalstudy AT eavess postoperativeoutcomesfollowingtrabeculectomyandnonpenetratingsurgicalproceduresa5yearlongitudinalstudy AT dhillonn postoperativeoutcomesfollowingtrabeculectomyandnonpenetratingsurgicalproceduresa5yearlongitudinalstudy AT ranjitp postoperativeoutcomesfollowingtrabeculectomyandnonpenetratingsurgicalproceduresa5yearlongitudinalstudy
_version_	1718402790647136256

Postoperative outcomes following trabeculectomy and nonpenetrating surgical procedures: a 5-year longitudinal study

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