Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

LDL receptor-related protein 1 (LRP1) is an endocytic receptor involved in cell signalling and energy homeostasis. Here Maoet al. demonstrate that endothelial Lrp1 modulates lipid and glucose metabolism by binding the nuclear receptor Pparγ and promoting its transcriptional activity.

Guardado en:
Detalles Bibliográficos
Autores principales: Hua Mao, Pamela Lockyer, Luge Li, Christie M. Ballantyne, Cam Patterson, Liang Xie, Xinchun Pi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9568598d8eac4446926e96a6f3554058
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares