Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus

Lupus pathogenesis is associated with high type 1 interferon stimulated gene (ISG) expression. Here, the authors correlate ISG expression in CD8+ T cells from lupus nephritis patients with abnormal mitochondrial function, implicating increased NAD consumption and reduced cell viability in the pathog...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Norzawani Buang, Lunnathaya Tapeng, Victor Gray, Alessandro Sardini, Chad Whilding, Liz Lightstone, Thomas D. Cairns, Matthew C. Pickering, Jacques Behmoaras, Guang Sheng Ling, Marina Botto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/956b2c52bede4e939180a254c3701f31
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares