HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome

HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome

Abstract Colorectal cancer (CRC) is one of the most lethal malignancies. The extreme heterogeneity in survival rate is driving the need for new prognostic biomarkers. Human endogenous retroviruses (hERVs) have been suggested to influence tumor progression, oncogenesis and elicit an immune response....

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Autores principales: Mahdi Golkaram, Michael L. Salmans, Shannon Kaplan, Raakhee Vijayaraghavan, Marta Martins, Nafeesa Khan, Cassandra Garbutt, Aaron Wise, Joyee Yao, Sandra Casimiro, Catarina Abreu, Daniela Macedo, Ana Lúcia Costa, Cecília Alvim, André Mansinho, Pedro Filipe, Pedro Marques da Costa, Afonso Fernandes, Paula Borralho, Cristina Ferreira, Fernando Aldeia, João Malaquias, Jim Godsey, Alex So, Traci Pawlowski, Luis Costa, Shile Zhang, Li Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/957481dcdc6e4e478acc8a847c3b62c1
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