Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis

Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.

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Detalles Bibliográficos
Autores principales: Omar Rifaie-Graham, Jonas Pollard, Samuel Raccio, Sandor Balog, Sebastian Rusch, María Andrea Hernández-Castañeda, Pierre-Yves Mantel, Hans-Peter Beck, Nico Bruns
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9576f1bf3fad4058b6e4acada8b6be9d
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Sumario:Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.