Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis

Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.

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Autores principales:	Omar Rifaie-Graham, Jonas Pollard, Samuel Raccio, Sandor Balog, Sebastian Rusch, María Andrea Hernández-Castañeda, Pierre-Yves Mantel, Hans-Peter Beck, Nico Bruns
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9576f1bf3fad4058b6e4acada8b6be9d
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spelling	oai:doaj.org-article:9576f1bf3fad4058b6e4acada8b6be9d2021-12-02T17:01:33ZHemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis10.1038/s41467-019-09122-z2041-1723https://doaj.org/article/9576f1bf3fad4058b6e4acada8b6be9d2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09122-zhttps://doaj.org/toc/2041-1723Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.Omar Rifaie-GrahamJonas PollardSamuel RaccioSandor BalogSebastian RuschMaría Andrea Hernández-CastañedaPierre-Yves MantelHans-Peter BeckNico BrunsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Omar Rifaie-Graham Jonas Pollard Samuel Raccio Sandor Balog Sebastian Rusch María Andrea Hernández-Castañeda Pierre-Yves Mantel Hans-Peter Beck Nico Bruns Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
description	Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.
format	article
author	Omar Rifaie-Graham Jonas Pollard Samuel Raccio Sandor Balog Sebastian Rusch María Andrea Hernández-Castañeda Pierre-Yves Mantel Hans-Peter Beck Nico Bruns
author_facet	Omar Rifaie-Graham Jonas Pollard Samuel Raccio Sandor Balog Sebastian Rusch María Andrea Hernández-Castañeda Pierre-Yves Mantel Hans-Peter Beck Nico Bruns
author_sort	Omar Rifaie-Graham
title	Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
title_short	Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
title_full	Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
title_fullStr	Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
title_full_unstemmed	Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
title_sort	hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9576f1bf3fad4058b6e4acada8b6be9d
work_keys_str_mv	AT omarrifaiegraham hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT jonaspollard hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT samuelraccio hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT sandorbalog hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT sebastianrusch hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT mariaandreahernandezcastaneda hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT pierreyvesmantel hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT hanspeterbeck hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis AT nicobruns hemozoincatalyzedprecipitationpolymerizationasanassayformalariadiagnosis
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Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis

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