Drug interactions and possible serotonin syndrome in a patient with fibromyalgia

Depression associated with fibromyalgia can be treated with selective serotonin reuptake inhibitors (SSRI) as fluoxetine, paroxetine or citalopram; or with serotonin–norepinephrine reuptake inhibitors (duloxetine or milnacipran). In patients with fibromyalgia, several meta-analyses have demonstrate...

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Autores principales: Patricia de Carvalho MASTROIANNI, Fabiana Rossi VARALLO, Manuel MACHUCA
Formato: article
Lenguaje:EN
Publicado: Universidad de Antioquia 2014
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Acceso en línea:https://doaj.org/article/957d823b89434f538b61c7e8109ca983
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Sumario:Depression associated with fibromyalgia can be treated with selective serotonin reuptake inhibitors (SSRI) as fluoxetine, paroxetine or citalopram; or with serotonin–norepinephrine reuptake inhibitors (duloxetine or milnacipran). In patients with fibromyalgia, several meta-analyses have demonstrated the effectiveness of antidepressants, particularly the tricyclic antidepressant (TCA) amitriptyline, which reduce the pain, fatigue, depression, and sleep disturbances. Additionally, tramadol, pregabalin, and gabapentin are other treatment options.