The dCache Chemoreceptor TlpA of <named-content content-type="genus-species">Helicobacter pylori</named-content> Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites

The dCache Chemoreceptor TlpA of <named-content content-type="genus-species">Helicobacter pylori</named-content> Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites

ABSTRACT The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1 domain, a structure that is capable of sensing many ligands; however, the only characterized TlpA signals are arginine, bicarbonate, an...

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Autores principales: Kevin S. Johnson, Bassam A. Elgamoudi, Freda E.-C. Jen, Christopher J. Day, Emily Goers Sweeney, Megan L. Pryce, Karen Guillemin, Thomas Haselhorst, Victoria Korolik, Karen M. Ottemann
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Helicobacter pylori
chemotaxis
ligand discovery
dCache
signal transduction
chemoreceptor
Microbiology
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Acceso en línea:https://doaj.org/article/958587dd065b4f2d967bac45ac018790
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