Large-scale lipid analysis with C=C location and sn-position isomer resolving power
Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological sampl...
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Nature Portfolio
2020
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oai:doaj.org-article:958674d139614cdfbb1d84c75b508bab2021-12-02T13:23:48ZLarge-scale lipid analysis with C=C location and sn-position isomer resolving power10.1038/s41467-019-14180-42041-1723https://doaj.org/article/958674d139614cdfbb1d84c75b508bab2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14180-4https://doaj.org/toc/2041-1723Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological samples.Wenbo CaoSimin ChengJing YangJiaxin FengWenpeng ZhangZishuai LiQinhua ChenYu XiaZheng OuyangXiaoxiao MaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Wenbo Cao Simin Cheng Jing Yang Jiaxin Feng Wenpeng Zhang Zishuai Li Qinhua Chen Yu Xia Zheng Ouyang Xiaoxiao Ma Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
description |
Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological samples. |
format |
article |
author |
Wenbo Cao Simin Cheng Jing Yang Jiaxin Feng Wenpeng Zhang Zishuai Li Qinhua Chen Yu Xia Zheng Ouyang Xiaoxiao Ma |
author_facet |
Wenbo Cao Simin Cheng Jing Yang Jiaxin Feng Wenpeng Zhang Zishuai Li Qinhua Chen Yu Xia Zheng Ouyang Xiaoxiao Ma |
author_sort |
Wenbo Cao |
title |
Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
title_short |
Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
title_full |
Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
title_fullStr |
Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
title_full_unstemmed |
Large-scale lipid analysis with C=C location and sn-position isomer resolving power |
title_sort |
large-scale lipid analysis with c=c location and sn-position isomer resolving power |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/958674d139614cdfbb1d84c75b508bab |
work_keys_str_mv |
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1718393167347187712 |