Large-scale lipid analysis with C=C location and sn-position isomer resolving power

Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological sampl...

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Autores principales: Wenbo Cao, Simin Cheng, Jing Yang, Jiaxin Feng, Wenpeng Zhang, Zishuai Li, Qinhua Chen, Yu Xia, Zheng Ouyang, Xiaoxiao Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/958674d139614cdfbb1d84c75b508bab
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spelling oai:doaj.org-article:958674d139614cdfbb1d84c75b508bab2021-12-02T13:23:48ZLarge-scale lipid analysis with C=C location and sn-position isomer resolving power10.1038/s41467-019-14180-42041-1723https://doaj.org/article/958674d139614cdfbb1d84c75b508bab2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14180-4https://doaj.org/toc/2041-1723Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological samples.Wenbo CaoSimin ChengJing YangJiaxin FengWenpeng ZhangZishuai LiQinhua ChenYu XiaZheng OuyangXiaoxiao MaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wenbo Cao
Simin Cheng
Jing Yang
Jiaxin Feng
Wenpeng Zhang
Zishuai Li
Qinhua Chen
Yu Xia
Zheng Ouyang
Xiaoxiao Ma
Large-scale lipid analysis with C=C location and sn-position isomer resolving power
description Coupling photochemical derivatization with tandem mass spectrometry enables C=C-isomer resolved lipidomics. Here, the authors further develop this approach into a shotgun lipidomics workflow that allows simultaneous characterization of lipid C=C locations and sn-positions in complex biological samples.
format article
author Wenbo Cao
Simin Cheng
Jing Yang
Jiaxin Feng
Wenpeng Zhang
Zishuai Li
Qinhua Chen
Yu Xia
Zheng Ouyang
Xiaoxiao Ma
author_facet Wenbo Cao
Simin Cheng
Jing Yang
Jiaxin Feng
Wenpeng Zhang
Zishuai Li
Qinhua Chen
Yu Xia
Zheng Ouyang
Xiaoxiao Ma
author_sort Wenbo Cao
title Large-scale lipid analysis with C=C location and sn-position isomer resolving power
title_short Large-scale lipid analysis with C=C location and sn-position isomer resolving power
title_full Large-scale lipid analysis with C=C location and sn-position isomer resolving power
title_fullStr Large-scale lipid analysis with C=C location and sn-position isomer resolving power
title_full_unstemmed Large-scale lipid analysis with C=C location and sn-position isomer resolving power
title_sort large-scale lipid analysis with c=c location and sn-position isomer resolving power
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/958674d139614cdfbb1d84c75b508bab
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