Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly and centrosome microtubule anchoring.

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Autores principales:	Ning Huang, Yuqing Xia, Donghui Zhang, Song Wang, Yitian Bao, Runsheng He, Junlin Teng, Jianguo Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/95869170b06f433aa908d61ffb11272f
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spelling	oai:doaj.org-article:95869170b06f433aa908d61ffb11272f2021-12-02T17:06:03ZHierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC6810.1038/ncomms150572041-1723https://doaj.org/article/95869170b06f433aa908d61ffb11272f2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15057https://doaj.org/toc/2041-1723Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly and centrosome microtubule anchoring.Ning HuangYuqing XiaDonghui ZhangSong WangYitian BaoRunsheng HeJunlin TengJianguo ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ning Huang Yuqing Xia Donghui Zhang Song Wang Yitian Bao Runsheng He Junlin Teng Jianguo Chen Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
description	Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly and centrosome microtubule anchoring.
format	article
author	Ning Huang Yuqing Xia Donghui Zhang Song Wang Yitian Bao Runsheng He Junlin Teng Jianguo Chen
author_facet	Ning Huang Yuqing Xia Donghui Zhang Song Wang Yitian Bao Runsheng He Junlin Teng Jianguo Chen
author_sort	Ning Huang
title	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
title_short	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
title_full	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
title_fullStr	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
title_full_unstemmed	Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
title_sort	hierarchical assembly of centriole subdistal appendages via centrosome binding proteins ccdc120 and ccdc68
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/95869170b06f433aa908d61ffb11272f
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Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

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