Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis

Objective. This review aimed at systematically evaluating the efficacy and safety of moxibustion for chronic fatigue syndrome (CFS). Methods. Relevant trials were searched in seven digital databases up to January 2021. After literature screening, data extraction, and literature quality evaluation, t...

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Autores principales:	Jianyu You, Jing Ye, Haiyan Li, Wenguo Ye, Ensi Hong
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/9590da2638a94a0bb55b7cc5f8888776
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spelling	oai:doaj.org-article:9590da2638a94a0bb55b7cc5f88887762021-11-22T01:10:47ZMoxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis1741-428810.1155/2021/6418217https://doaj.org/article/9590da2638a94a0bb55b7cc5f88887762021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6418217https://doaj.org/toc/1741-4288Objective. This review aimed at systematically evaluating the efficacy and safety of moxibustion for chronic fatigue syndrome (CFS). Methods. Relevant trials were searched in seven digital databases up to January 2021. After literature screening, data extraction, and literature quality evaluation, the included studies were meta-analyzed using RevMan 5.4 software. The evidence level was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results. Fifteen studies involving 1030 CFS participants were included. Meta-analyses showed a favorable effect of moxibustion on the total effective rate compared with acupuncture (OR = 4.58, 95%CI = [2.85, 7.35], P<0.00001) and drugs (OR = 6.36, 95%CI = [3.48, 11.59], P<0.00001). Moxibustion also appeared to significantly reduce fatigue severity measured by fatigue scale-14 (FS-14) (WMD = −2.20, 95% CI = [−3.16, −1.24], P<0.00001) and fatigue assessment instrument (FAI) (WMD = −16.36, 95% CI = [−26.58, −6.14], P=0.002) compared with the control group. In addition, among the 15 included studies, only two studies reported adverse events related to moxibustion, and the symptoms were relatively mild. The quality of evidence based on the 15 included trials was assessed as moderate to very low. Conclusions. Based on limited evidence, moxibustion might be an effective and safe complementary therapy for CFS, which can be recommended to manage CFS. Because of the limited level of evidence in this review, further high-quality trials are still needed to confirm these findings.Jianyu YouJing YeHaiyan LiWenguo YeEnsi HongHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Jianyu You Jing Ye Haiyan Li Wenguo Ye Ensi Hong Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
description	Objective. This review aimed at systematically evaluating the efficacy and safety of moxibustion for chronic fatigue syndrome (CFS). Methods. Relevant trials were searched in seven digital databases up to January 2021. After literature screening, data extraction, and literature quality evaluation, the included studies were meta-analyzed using RevMan 5.4 software. The evidence level was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results. Fifteen studies involving 1030 CFS participants were included. Meta-analyses showed a favorable effect of moxibustion on the total effective rate compared with acupuncture (OR = 4.58, 95%CI = [2.85, 7.35], P<0.00001) and drugs (OR = 6.36, 95%CI = [3.48, 11.59], P<0.00001). Moxibustion also appeared to significantly reduce fatigue severity measured by fatigue scale-14 (FS-14) (WMD = −2.20, 95% CI = [−3.16, −1.24], P<0.00001) and fatigue assessment instrument (FAI) (WMD = −16.36, 95% CI = [−26.58, −6.14], P=0.002) compared with the control group. In addition, among the 15 included studies, only two studies reported adverse events related to moxibustion, and the symptoms were relatively mild. The quality of evidence based on the 15 included trials was assessed as moderate to very low. Conclusions. Based on limited evidence, moxibustion might be an effective and safe complementary therapy for CFS, which can be recommended to manage CFS. Because of the limited level of evidence in this review, further high-quality trials are still needed to confirm these findings.
format	article
author	Jianyu You Jing Ye Haiyan Li Wenguo Ye Ensi Hong
author_facet	Jianyu You Jing Ye Haiyan Li Wenguo Ye Ensi Hong
author_sort	Jianyu You
title	Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
title_short	Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
title_full	Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
title_fullStr	Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
title_full_unstemmed	Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis
title_sort	moxibustion for chronic fatigue syndrome: a systematic review and meta-analysis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/9590da2638a94a0bb55b7cc5f8888776
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Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis

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