Linear mapping approximation of gene regulatory networks with stochastic dynamics

The intractability of most stochastic models of gene regulatory networks (GRNs) limits their utility. Here, the authors present a linear-mapping approximation mapping models onto simpler ones, giving approximate but accurate analytic or semi- analytic solutions for a wide range of model GRNs.

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Detalles Bibliográficos
Autores principales:	Zhixing Cao, Ramon Grima
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/959a6486a2594874837b30b8d6153b6a
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spelling	oai:doaj.org-article:959a6486a2594874837b30b8d6153b6a2021-12-02T14:38:51ZLinear mapping approximation of gene regulatory networks with stochastic dynamics10.1038/s41467-018-05822-02041-1723https://doaj.org/article/959a6486a2594874837b30b8d6153b6a2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05822-0https://doaj.org/toc/2041-1723The intractability of most stochastic models of gene regulatory networks (GRNs) limits their utility. Here, the authors present a linear-mapping approximation mapping models onto simpler ones, giving approximate but accurate analytic or semi- analytic solutions for a wide range of model GRNs.Zhixing CaoRamon GrimaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhixing Cao Ramon Grima Linear mapping approximation of gene regulatory networks with stochastic dynamics
description	The intractability of most stochastic models of gene regulatory networks (GRNs) limits their utility. Here, the authors present a linear-mapping approximation mapping models onto simpler ones, giving approximate but accurate analytic or semi- analytic solutions for a wide range of model GRNs.
format	article
author	Zhixing Cao Ramon Grima
author_facet	Zhixing Cao Ramon Grima
author_sort	Zhixing Cao
title	Linear mapping approximation of gene regulatory networks with stochastic dynamics
title_short	Linear mapping approximation of gene regulatory networks with stochastic dynamics
title_full	Linear mapping approximation of gene regulatory networks with stochastic dynamics
title_fullStr	Linear mapping approximation of gene regulatory networks with stochastic dynamics
title_full_unstemmed	Linear mapping approximation of gene regulatory networks with stochastic dynamics
title_sort	linear mapping approximation of gene regulatory networks with stochastic dynamics
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/959a6486a2594874837b30b8d6153b6a
work_keys_str_mv	AT zhixingcao linearmappingapproximationofgeneregulatorynetworkswithstochasticdynamics AT ramongrima linearmappingapproximationofgeneregulatorynetworkswithstochasticdynamics
_version_	1718390850866642944

Linear mapping approximation of gene regulatory networks with stochastic dynamics

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