C1q/TNF-related protein-9 ameliorates hypoxia-induced pulmonary hypertension by regulating secretion of endothelin-1 and nitric oxide mediated by AMPK in rats
Abstract Injury/dysfunction of the endothelium of pulmonary arteries contributes to hypoxia-induced pulmonary hypertension (HPH). We investigated whether C1q/tumor necrosis factor-related protein-9 (CTRP9), a newly identified cardiovascular agent, has protective roles in the development of HPH. HPH...
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Main Authors: | Qiaoyan Jin, Hui Su, Rui Yang, Yanzhen Tan, Buying Li, Wei Yi, Qianqian Dong, Haifeng Zhang, Wenjuan Xing, Xin Sun |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/95aa1ae4c90e4da9a8ceb92cb5671961 |
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