I(nsp1)ecting SARS-CoV-2–ribosome interactions

Simeoni et al discuss how recent structural work has improved our understanding of SARS-CoV-2 Nsp1-mediated translation inhibition and how Nsp1 inhibition could impact host immune responses and suppress viral replication.

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Detalles Bibliográficos
Autores principales: Matthieu Simeoni, Théo Cavinato, Daniel Rodriguez, David Gatfield
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/95ad0b94a72a4804a968908812907988
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Descripción
Sumario:Simeoni et al discuss how recent structural work has improved our understanding of SARS-CoV-2 Nsp1-mediated translation inhibition and how Nsp1 inhibition could impact host immune responses and suppress viral replication.