Effect of vitamin D and interferon α-2b on cytokine profile in pregnant women with vaginal infections
A study was conducted to evaluate effectiveness of vitamin D and interferon α-2b preparations on cytokine profile in pregnant women with vaginal infections. It was shown that pregnant women with vs. without bacterial vaginosis were featured with low vitamin D level in 53.8–60.5% cases. Administratio...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | RU |
| Published: |
Sankt-Peterburg : NIIÈM imeni Pastera
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/95b57d00aaee4fef86890c598c9ed210 |
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| Summary: | A study was conducted to evaluate effectiveness of vitamin D and interferon α-2b preparations on cytokine profile in pregnant women with vaginal infections. It was shown that pregnant women with vs. without bacterial vaginosis were featured with low vitamin D level in 53.8–60.5% cases. Administration of vitamin D and interferon α-2b preparations in combination with antibacterial therapy in pregnant women with bacterial vaginosis conferred anti-inflammatory effect resulting in normalized IL-8 level corresponding to that one in healthy subjects. Use of vitamin D altered interferon status and augmented antimicrobial activity in pregnant women confirmed by reduced rate of ARI episodes. |
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