Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron µCT study.

Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron µCT study.

Osteonecrosis of the jaw, in association with bisphosphonates (BRONJ) used for treating osteoporosis or cancer, is a severe and most often irreversible side effect whose underlying pathophysiological mechanisms remain largely unknown. Osteocytes are involved in bone remodeling and mineralization whe...

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Autores principales: Bernhard Hesse, Max Langer, Peter Varga, Alexandra Pacureanu, Pei Dong, Susanne Schrof, Nils Männicke, Heikki Suhonen, Cecile Olivier, Peter Maurer, Galateia J Kazakia, Kay Raum, Francoise Peyrin
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/95b5d9f4dd4b46e7bad1dc26f90fd63a
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