PROMOTER POLYMORPHISM -857С>T OF TNFα GENE AND EFFICACY OF ANTICYTOKINE THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS
Abstract. Prevalence of TNFα gene promoter polymorphism at -857 position was investigated in normal persons and among patients with rheumatoid arthritis. We detected a relation of this polymorphism to the levels of TNFα production by mononuclear cells of healthy donors. Changes in relative frequenci...
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Autores principales: | A. N. Silkov, N. S. Shkaruba, T. A. Kalashnikova, L. P. Sizyakina, J. B. Shulman, S. V. Dolgikh, V. I. Mazurov, O. A. Gerzog, A. E. Sizikov, V. A. Kozlov, S. V. Sennikov |
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Formato: | article |
Lenguaje: | RU |
Publicado: |
SPb RAACI
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/95b6b45dc0704e0f90fa95372ca01f96 |
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