Optimizing screening procedures for early detection of glycemic disorders

Aim. To estimate the actual prevalence of type 2 diabetes mellitus (T2DM) and prediabetes in individuals at high risk for T2DM and to develop an optimized stepwise screening procedure. Materials and Methods. A mobile diagnostic unit conducted outpatient screening for glycemic disorders. First stag...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Inna Vladimirovna Misnikova, Alexander Vasil'evich Dreval, Yulia Alexandrovna Kovaleva, Valeria Alekseevna Gubkina, Tatiana Sergeevna Lakeeva
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2014
Materias:
Acceso en línea:https://doaj.org/article/95b78681b199420f9937a6b25e64908d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:95b78681b199420f9937a6b25e64908d
record_format dspace
spelling oai:doaj.org-article:95b78681b199420f9937a6b25e64908d2021-11-14T09:00:18ZOptimizing screening procedures for early detection of glycemic disorders2072-03512072-037810.14341/DM201418-14https://doaj.org/article/95b78681b199420f9937a6b25e64908d2014-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6305https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To estimate the actual prevalence of type 2 diabetes mellitus (T2DM) and prediabetes in individuals at high risk for T2DM and to develop an optimized stepwise screening procedure. Materials and Methods. A mobile diagnostic unit conducted outpatient screening for glycemic disorders. First stage of the survey included distribution of the FINDRISK questionnaire within the target subpopulation. At the second stage, study groups were formed based on the acquired data. Third stage involved clinical evaluation of glucose homeostasis by testing HbA1c levels and performing oral glucose tolerance test (OGTT). Individuals considered at high risk for development of T2DM were referred to specialized educational programs. A total of 2200 subjects were included in the present survey. In 1377 cases OGTT was supplemented with the testing of HbA1c. Statistical processing of the data was performed with Microsoft Excel software utility. Results. The interpretation of OGTT results identified 53.5% (n=1176) of study subjects as positive for glycemic disorders: 26.7% (n=587) with T2DM and 26.8% (n=589) with prediabetes, respectively. Impaired glucose tolerance was detected in 12.1% (n=266), impaired fasting glucose ? in 9.1% (n=199), and the combination of these two conditions ? in 5.6% (n=124) of examined individuals, respectively. In 235 subjects (17.1%) T2DM was diagnosed by means of HbA1c testing. 45% of examined individuals (n=620) had HbA1cInna Vladimirovna MisnikovaAlexander Vasil'evich DrevalYulia Alexandrovna KovalevaValeria Alekseevna GubkinaTatiana Sergeevna LakeevaEndocrinology Research Centrearticletype 2 diabetes mellitusprediabetesfindriskoral glucose tolerance testNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 17, Iss 1, Pp 8-14 (2014)
institution DOAJ
collection DOAJ
language EN
RU
topic type 2 diabetes mellitus
prediabetes
findrisk
oral glucose tolerance test
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle type 2 diabetes mellitus
prediabetes
findrisk
oral glucose tolerance test
Nutritional diseases. Deficiency diseases
RC620-627
Inna Vladimirovna Misnikova
Alexander Vasil'evich Dreval
Yulia Alexandrovna Kovaleva
Valeria Alekseevna Gubkina
Tatiana Sergeevna Lakeeva
Optimizing screening procedures for early detection of glycemic disorders
description Aim. To estimate the actual prevalence of type 2 diabetes mellitus (T2DM) and prediabetes in individuals at high risk for T2DM and to develop an optimized stepwise screening procedure. Materials and Methods. A mobile diagnostic unit conducted outpatient screening for glycemic disorders. First stage of the survey included distribution of the FINDRISK questionnaire within the target subpopulation. At the second stage, study groups were formed based on the acquired data. Third stage involved clinical evaluation of glucose homeostasis by testing HbA1c levels and performing oral glucose tolerance test (OGTT). Individuals considered at high risk for development of T2DM were referred to specialized educational programs. A total of 2200 subjects were included in the present survey. In 1377 cases OGTT was supplemented with the testing of HbA1c. Statistical processing of the data was performed with Microsoft Excel software utility. Results. The interpretation of OGTT results identified 53.5% (n=1176) of study subjects as positive for glycemic disorders: 26.7% (n=587) with T2DM and 26.8% (n=589) with prediabetes, respectively. Impaired glucose tolerance was detected in 12.1% (n=266), impaired fasting glucose ? in 9.1% (n=199), and the combination of these two conditions ? in 5.6% (n=124) of examined individuals, respectively. In 235 subjects (17.1%) T2DM was diagnosed by means of HbA1c testing. 45% of examined individuals (n=620) had HbA1c
format article
author Inna Vladimirovna Misnikova
Alexander Vasil'evich Dreval
Yulia Alexandrovna Kovaleva
Valeria Alekseevna Gubkina
Tatiana Sergeevna Lakeeva
author_facet Inna Vladimirovna Misnikova
Alexander Vasil'evich Dreval
Yulia Alexandrovna Kovaleva
Valeria Alekseevna Gubkina
Tatiana Sergeevna Lakeeva
author_sort Inna Vladimirovna Misnikova
title Optimizing screening procedures for early detection of glycemic disorders
title_short Optimizing screening procedures for early detection of glycemic disorders
title_full Optimizing screening procedures for early detection of glycemic disorders
title_fullStr Optimizing screening procedures for early detection of glycemic disorders
title_full_unstemmed Optimizing screening procedures for early detection of glycemic disorders
title_sort optimizing screening procedures for early detection of glycemic disorders
publisher Endocrinology Research Centre
publishDate 2014
url https://doaj.org/article/95b78681b199420f9937a6b25e64908d
work_keys_str_mv AT innavladimirovnamisnikova optimizingscreeningproceduresforearlydetectionofglycemicdisorders
AT alexandervasilevichdreval optimizingscreeningproceduresforearlydetectionofglycemicdisorders
AT yuliaalexandrovnakovaleva optimizingscreeningproceduresforearlydetectionofglycemicdisorders
AT valeriaalekseevnagubkina optimizingscreeningproceduresforearlydetectionofglycemicdisorders
AT tatianasergeevnalakeeva optimizingscreeningproceduresforearlydetectionofglycemicdisorders
_version_ 1718429595547467776