Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.
<h4>Background</h4>Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK)-Signal transducer and activator of transcription (STAT) pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To...
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Autores principales: | Clifford Liongue, Lynda A O'Sullivan, Monique C Trengove, Alister C Ward |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/95bb0633bf5e47cca844c3fec3a56a3c |
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