Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes

The function on subgenomic flaviviral RNA (sfRNA) in the mosquito vector is not well understood. Here, Slonchak et al. show that sfRNA affects virus-induced apoptosis and dissemination of ZIKV in Aedes aegypti mosquitoes, suggesting a role of sfRNA in Zika virus replication and transmission.

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Autores principales:	Andrii Slonchak, Leon E. Hugo, Morgan E. Freney, Sonja Hall-Mendelin, Alberto A. Amarilla, Francisco J. Torres, Yin Xiang Setoh, Nias Y. G. Peng, Julian D. J. Sng, Roy A. Hall, Andrew F. van den Hurk, Gregor J. Devine, Alexander A. Khromykh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/95cc3ef3f6434f148f53dccae4ece433
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spelling	oai:doaj.org-article:95cc3ef3f6434f148f53dccae4ece4332021-12-02T15:39:18ZZika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes10.1038/s41467-020-16086-y2041-1723https://doaj.org/article/95cc3ef3f6434f148f53dccae4ece4332020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16086-yhttps://doaj.org/toc/2041-1723The function on subgenomic flaviviral RNA (sfRNA) in the mosquito vector is not well understood. Here, Slonchak et al. show that sfRNA affects virus-induced apoptosis and dissemination of ZIKV in Aedes aegypti mosquitoes, suggesting a role of sfRNA in Zika virus replication and transmission.Andrii SlonchakLeon E. HugoMorgan E. FreneySonja Hall-MendelinAlberto A. AmarillaFrancisco J. TorresYin Xiang SetohNias Y. G. PengJulian D. J. SngRoy A. HallAndrew F. van den HurkGregor J. DevineAlexander A. KhromykhNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrii Slonchak Leon E. Hugo Morgan E. Freney Sonja Hall-Mendelin Alberto A. Amarilla Francisco J. Torres Yin Xiang Setoh Nias Y. G. Peng Julian D. J. Sng Roy A. Hall Andrew F. van den Hurk Gregor J. Devine Alexander A. Khromykh Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
description	The function on subgenomic flaviviral RNA (sfRNA) in the mosquito vector is not well understood. Here, Slonchak et al. show that sfRNA affects virus-induced apoptosis and dissemination of ZIKV in Aedes aegypti mosquitoes, suggesting a role of sfRNA in Zika virus replication and transmission.
format	article
author	Andrii Slonchak Leon E. Hugo Morgan E. Freney Sonja Hall-Mendelin Alberto A. Amarilla Francisco J. Torres Yin Xiang Setoh Nias Y. G. Peng Julian D. J. Sng Roy A. Hall Andrew F. van den Hurk Gregor J. Devine Alexander A. Khromykh
author_facet	Andrii Slonchak Leon E. Hugo Morgan E. Freney Sonja Hall-Mendelin Alberto A. Amarilla Francisco J. Torres Yin Xiang Setoh Nias Y. G. Peng Julian D. J. Sng Roy A. Hall Andrew F. van den Hurk Gregor J. Devine Alexander A. Khromykh
author_sort	Andrii Slonchak
title	Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
title_short	Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
title_full	Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
title_fullStr	Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
title_full_unstemmed	Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
title_sort	zika virus noncoding rna suppresses apoptosis and is required for virus transmission by mosquitoes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/95cc3ef3f6434f148f53dccae4ece433
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Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes

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