Diagnostic accuracy of squash cytology in central nervous system tumors

Introduction: CNS tumor requires intraoperative decision making regarding the extent of tumor removal. Clinical examination and imaging studies are not sufficient enough to predict the biological behavior of the tumors. Squash cytology is a quick method of evaluation of cytomorphologic features pre...

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Autores principales:	Ram Kumar Shrestha, Bibek KC, Gopal Sedain, Gita Sayami, Sushil Shilpakar, Mohan Raj Sharma, Amit Bahadur Pradhanang, Prakash Kafle, Binod Rajbhandari
Formato:	article
Lenguaje:	EN
Publicado:	Society of Surgeons of Nepal 2017
Materias:	CNS tumor Gliomas Surgery RD1-811
Acceso en línea:	https://doaj.org/article/95d091e191874e12aece92725d276ae8
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spelling	oai:doaj.org-article:95d091e191874e12aece92725d276ae82021-12-05T19:16:14ZDiagnostic accuracy of squash cytology in central nervous system tumors10.3126/jssn.v20i1.243831815-39842392-4772https://doaj.org/article/95d091e191874e12aece92725d276ae82017-06-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/24383https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: CNS tumor requires intraoperative decision making regarding the extent of tumor removal. Clinical examination and imaging studies are not sufficient enough to predict the biological behavior of the tumors. Squash cytology is a quick method of evaluation of cytomorphologic features prepared from smear technique and provide the preliminary diagnosis and aid in intraoperative decision making by differentiating neoplastic from non neoplastic and benign from malignant lesions. The aim of this study is compare the diagnostic accuracy of squash cytology to that of histopathological examination. Methods: This study consists of 36 specimens from both brain and spine subjected to both squash cytology and histopathological evaluation. The squash preparation and histopathological finding were later compared and diagnostic accuracy calculated. Results: Gliomas are the most common tumor encountered and the accuracy of Squash cytology obtained was 71%. In meningioma, 100% diagnostic accuracy was obtained however, there was limitation in accurately predict the subgroup of tumor by squash cytology alone. Other neoplastic lesions included in this study were Schwannoma, Oligodendroglioma, Ependymoma, mixed tumors and others. Overall, the accuracy predicted by squash cytology is found to be 77.8 % in this study. Conclusion: Squash cytology is rapid and reliable method of tissue diagnosis that aid in intraoperative decision making regarding the extent of Central Nervous System tumor excision Ram Kumar ShresthaBibek KCGopal SedainGita SayamiSushil ShilpakarMohan Raj SharmaAmit Bahadur PradhanangPrakash KafleBinod RajbhandariSociety of Surgeons of NepalarticleCNS tumorGliomasSurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 20, Iss 1 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	CNS tumor Gliomas Surgery RD1-811
spellingShingle	CNS tumor Gliomas Surgery RD1-811 Ram Kumar Shrestha Bibek KC Gopal Sedain Gita Sayami Sushil Shilpakar Mohan Raj Sharma Amit Bahadur Pradhanang Prakash Kafle Binod Rajbhandari Diagnostic accuracy of squash cytology in central nervous system tumors
description	Introduction: CNS tumor requires intraoperative decision making regarding the extent of tumor removal. Clinical examination and imaging studies are not sufficient enough to predict the biological behavior of the tumors. Squash cytology is a quick method of evaluation of cytomorphologic features prepared from smear technique and provide the preliminary diagnosis and aid in intraoperative decision making by differentiating neoplastic from non neoplastic and benign from malignant lesions. The aim of this study is compare the diagnostic accuracy of squash cytology to that of histopathological examination. Methods: This study consists of 36 specimens from both brain and spine subjected to both squash cytology and histopathological evaluation. The squash preparation and histopathological finding were later compared and diagnostic accuracy calculated. Results: Gliomas are the most common tumor encountered and the accuracy of Squash cytology obtained was 71%. In meningioma, 100% diagnostic accuracy was obtained however, there was limitation in accurately predict the subgroup of tumor by squash cytology alone. Other neoplastic lesions included in this study were Schwannoma, Oligodendroglioma, Ependymoma, mixed tumors and others. Overall, the accuracy predicted by squash cytology is found to be 77.8 % in this study. Conclusion: Squash cytology is rapid and reliable method of tissue diagnosis that aid in intraoperative decision making regarding the extent of Central Nervous System tumor excision
format	article
author	Ram Kumar Shrestha Bibek KC Gopal Sedain Gita Sayami Sushil Shilpakar Mohan Raj Sharma Amit Bahadur Pradhanang Prakash Kafle Binod Rajbhandari
author_facet	Ram Kumar Shrestha Bibek KC Gopal Sedain Gita Sayami Sushil Shilpakar Mohan Raj Sharma Amit Bahadur Pradhanang Prakash Kafle Binod Rajbhandari
author_sort	Ram Kumar Shrestha
title	Diagnostic accuracy of squash cytology in central nervous system tumors
title_short	Diagnostic accuracy of squash cytology in central nervous system tumors
title_full	Diagnostic accuracy of squash cytology in central nervous system tumors
title_fullStr	Diagnostic accuracy of squash cytology in central nervous system tumors
title_full_unstemmed	Diagnostic accuracy of squash cytology in central nervous system tumors
title_sort	diagnostic accuracy of squash cytology in central nervous system tumors
publisher	Society of Surgeons of Nepal
publishDate	2017
url	https://doaj.org/article/95d091e191874e12aece92725d276ae8
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Diagnostic accuracy of squash cytology in central nervous system tumors

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