Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

Observationally, lower birthweight is a risk factor for cardiometabolic disease. Using Mendelian Randomization, the authors investigate whether maternal genetic factors that lower offspring birthweight also increase offspring cardiometabolic risk and show that the observational correlation is unlike...

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Autores principales:	Gunn-Helen Moen, Ben Brumpton, Cristen Willer, Bjørn Olav Åsvold, Kåre I. Birkeland, Geng Wang, Michael C. Neale, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Robert M. Kirkpatrick, Nicole M. Warrington, David M. Evans
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/95d285ad858b427cb6fd4144ad5c6065
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spelling	oai:doaj.org-article:95d285ad858b427cb6fd4144ad5c60652021-12-02T15:39:25ZMendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort10.1038/s41467-020-19257-z2041-1723https://doaj.org/article/95d285ad858b427cb6fd4144ad5c60652020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19257-zhttps://doaj.org/toc/2041-1723Observationally, lower birthweight is a risk factor for cardiometabolic disease. Using Mendelian Randomization, the authors investigate whether maternal genetic factors that lower offspring birthweight also increase offspring cardiometabolic risk and show that the observational correlation is unlikely to be due to the intrauterine environment.Gunn-Helen MoenBen BrumptonCristen WillerBjørn Olav ÅsvoldKåre I. BirkelandGeng WangMichael C. NealeRachel M. FreathyGeorge Davey SmithDeborah A. LawlorRobert M. KirkpatrickNicole M. WarringtonDavid M. EvansNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gunn-Helen Moen Ben Brumpton Cristen Willer Bjørn Olav Åsvold Kåre I. Birkeland Geng Wang Michael C. Neale Rachel M. Freathy George Davey Smith Deborah A. Lawlor Robert M. Kirkpatrick Nicole M. Warrington David M. Evans Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
description	Observationally, lower birthweight is a risk factor for cardiometabolic disease. Using Mendelian Randomization, the authors investigate whether maternal genetic factors that lower offspring birthweight also increase offspring cardiometabolic risk and show that the observational correlation is unlikely to be due to the intrauterine environment.
format	article
author	Gunn-Helen Moen Ben Brumpton Cristen Willer Bjørn Olav Åsvold Kåre I. Birkeland Geng Wang Michael C. Neale Rachel M. Freathy George Davey Smith Deborah A. Lawlor Robert M. Kirkpatrick Nicole M. Warrington David M. Evans
author_facet	Gunn-Helen Moen Ben Brumpton Cristen Willer Bjørn Olav Åsvold Kåre I. Birkeland Geng Wang Michael C. Neale Rachel M. Freathy George Davey Smith Deborah A. Lawlor Robert M. Kirkpatrick Nicole M. Warrington David M. Evans
author_sort	Gunn-Helen Moen
title	Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
title_short	Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
title_full	Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
title_fullStr	Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
title_full_unstemmed	Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
title_sort	mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the hunt cohort
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/95d285ad858b427cb6fd4144ad5c6065
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Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

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