Cryo-EM structure of the varicella-zoster virus A-capsid

Varicella-zoster virus (VZV) is the causative agent of chickenpox and herpes zoster (shingles). Cryo-EM structure of VZV capsid provides insights into the capsid assembly and reveals a pocket that could potentially be targeted by antiviral drugs.

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Autores principales: Junqing Sun, Congcong Liu, Ruchao Peng, Fu-Kun Zhang, Zhou Tong, Sheng Liu, Yi Shi, Zhennan Zhao, Wen-Bo Zeng, George Fu Gao, Hong-Jie Shen, Xiaoming Yang, Minhua Luo, Jianxun Qi, Peiyi Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/95e928e538d24faf846bda0680c0a5e0
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spelling oai:doaj.org-article:95e928e538d24faf846bda0680c0a5e02021-12-02T18:48:04ZCryo-EM structure of the varicella-zoster virus A-capsid10.1038/s41467-020-18537-y2041-1723https://doaj.org/article/95e928e538d24faf846bda0680c0a5e02020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18537-yhttps://doaj.org/toc/2041-1723Varicella-zoster virus (VZV) is the causative agent of chickenpox and herpes zoster (shingles). Cryo-EM structure of VZV capsid provides insights into the capsid assembly and reveals a pocket that could potentially be targeted by antiviral drugs.Junqing SunCongcong LiuRuchao PengFu-Kun ZhangZhou TongSheng LiuYi ShiZhennan ZhaoWen-Bo ZengGeorge Fu GaoHong-Jie ShenXiaoming YangMinhua LuoJianxun QiPeiyi WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Junqing Sun
Congcong Liu
Ruchao Peng
Fu-Kun Zhang
Zhou Tong
Sheng Liu
Yi Shi
Zhennan Zhao
Wen-Bo Zeng
George Fu Gao
Hong-Jie Shen
Xiaoming Yang
Minhua Luo
Jianxun Qi
Peiyi Wang
Cryo-EM structure of the varicella-zoster virus A-capsid
description Varicella-zoster virus (VZV) is the causative agent of chickenpox and herpes zoster (shingles). Cryo-EM structure of VZV capsid provides insights into the capsid assembly and reveals a pocket that could potentially be targeted by antiviral drugs.
format article
author Junqing Sun
Congcong Liu
Ruchao Peng
Fu-Kun Zhang
Zhou Tong
Sheng Liu
Yi Shi
Zhennan Zhao
Wen-Bo Zeng
George Fu Gao
Hong-Jie Shen
Xiaoming Yang
Minhua Luo
Jianxun Qi
Peiyi Wang
author_facet Junqing Sun
Congcong Liu
Ruchao Peng
Fu-Kun Zhang
Zhou Tong
Sheng Liu
Yi Shi
Zhennan Zhao
Wen-Bo Zeng
George Fu Gao
Hong-Jie Shen
Xiaoming Yang
Minhua Luo
Jianxun Qi
Peiyi Wang
author_sort Junqing Sun
title Cryo-EM structure of the varicella-zoster virus A-capsid
title_short Cryo-EM structure of the varicella-zoster virus A-capsid
title_full Cryo-EM structure of the varicella-zoster virus A-capsid
title_fullStr Cryo-EM structure of the varicella-zoster virus A-capsid
title_full_unstemmed Cryo-EM structure of the varicella-zoster virus A-capsid
title_sort cryo-em structure of the varicella-zoster virus a-capsid
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/95e928e538d24faf846bda0680c0a5e0
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