Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.

Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor acc...

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Autores principales:	Moo Jae Han, Seung Woo Yang, Sang Il Bae, Young Min Moon, Wan Jeon, Chul Won Choi, Sung Kwang Park, Jin Young Kim
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/95ecac52f7a44aba9c62bc9213e3bde6
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spelling	oai:doaj.org-article:95ecac52f7a44aba9c62bc9213e3bde62021-11-25T06:19:03ZEvaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.1932-620310.1371/journal.pone.0251441https://doaj.org/article/95ecac52f7a44aba9c62bc9213e3bde62021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251441https://doaj.org/toc/1932-6203Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (-0.074 cm) and 0.051 cm (-0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R50. Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.Moo Jae HanSeung Woo YangSang Il BaeYoung Min MoonWan JeonChul Won ChoiSung Kwang ParkJin Young KimPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 5, p e0251441 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Moo Jae Han Seung Woo Yang Sang Il Bae Young Min Moon Wan Jeon Chul Won Choi Sung Kwang Park Jin Young Kim Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
description	Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (-0.074 cm) and 0.051 cm (-0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R50. Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.
format	article
author	Moo Jae Han Seung Woo Yang Sang Il Bae Young Min Moon Wan Jeon Chul Won Choi Sung Kwang Park Jin Young Kim
author_facet	Moo Jae Han Seung Woo Yang Sang Il Bae Young Min Moon Wan Jeon Chul Won Choi Sung Kwang Park Jin Young Kim
author_sort	Moo Jae Han
title	Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
title_short	Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
title_full	Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
title_fullStr	Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
title_full_unstemmed	Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
title_sort	evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/95ecac52f7a44aba9c62bc9213e3bde6
work_keys_str_mv	AT moojaehan evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT seungwooyang evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT sangilbae evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT youngminmoon evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT wanjeon evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT chulwonchoi evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT sungkwangpark evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy AT jinyoungkim evaluationofmonoxidefilmbaseddosimetersforsurfacedosedetectioninelectrontherapy
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Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.

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