STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas

STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas

The mechanism underlying the dissemination of diffuse large B-cell lymphoma (DLBCL) is unclear. Here, the authors show that STAT3 controls amoeboid migration in DLBCL via the transcriptional activation of RHOH, which then releases RhoA from RhoGDIγ-mediated suppression, or via regulating microtubule...

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Autores principales: Yi-Ru Pan, Chih-Cheng Chen, Yu-Tien Chan, Hsiao-Jung Wang, Fan-Tso Chien, Yeng-Long Chen, Jing-Lan Liu, Muh-Hwa Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/95f73b88a6d342eb9cd45626c936f80a
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