Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

High-grade serous ovarian cancer is the most common and aggressive ovarian cancer, with uncertain cell of origin. Here, the authors undertake a mass spectrometric analysis of 26 cancer cell lines and identify a protein signature that classifies ovarian cancer tissues into epithelial and mesenchymal...

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Autores principales:	F. Coscia, K. M. Watters, M. Curtis, M. A. Eckert, C. Y. Chiang, S. Tyanova, A. Montag, R. R. Lastra, E. Lengyel, M. Mann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/95fa8f1cb72a47d29457dfe76f69b362
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spelling	oai:doaj.org-article:95fa8f1cb72a47d29457dfe76f69b3622021-12-02T16:58:24ZIntegrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status10.1038/ncomms126452041-1723https://doaj.org/article/95fa8f1cb72a47d29457dfe76f69b3622016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12645https://doaj.org/toc/2041-1723High-grade serous ovarian cancer is the most common and aggressive ovarian cancer, with uncertain cell of origin. Here, the authors undertake a mass spectrometric analysis of 26 cancer cell lines and identify a protein signature that classifies ovarian cancer tissues into epithelial and mesenchymal groups.F. CosciaK. M. WattersM. CurtisM. A. EckertC. Y. ChiangS. TyanovaA. MontagR. R. LastraE. LengyelM. MannNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q F. Coscia K. M. Watters M. Curtis M. A. Eckert C. Y. Chiang S. Tyanova A. Montag R. R. Lastra E. Lengyel M. Mann Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
description	High-grade serous ovarian cancer is the most common and aggressive ovarian cancer, with uncertain cell of origin. Here, the authors undertake a mass spectrometric analysis of 26 cancer cell lines and identify a protein signature that classifies ovarian cancer tissues into epithelial and mesenchymal groups.
format	article
author	F. Coscia K. M. Watters M. Curtis M. A. Eckert C. Y. Chiang S. Tyanova A. Montag R. R. Lastra E. Lengyel M. Mann
author_facet	F. Coscia K. M. Watters M. Curtis M. A. Eckert C. Y. Chiang S. Tyanova A. Montag R. R. Lastra E. Lengyel M. Mann
author_sort	F. Coscia
title	Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
title_short	Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
title_full	Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
title_fullStr	Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
title_full_unstemmed	Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
title_sort	integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/95fa8f1cb72a47d29457dfe76f69b362
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Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

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