Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

Glycan molecules can be modified directly on the cell surface via chemoenzymatic approaches. Here, the authors employ a set of four bacterial glycosyltransferases to develop a live cell-based killing assay to probe host cell glycan-mediated influenza A virus infection.

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Autores principales:	Senlian Hong, Yujie Shi, Nicholas C. Wu, Geramie Grande, Lacey Douthit, Hua Wang, Wen Zhou, K. Barry Sharpless, Ian A. Wilson, Jia Xie, Peng Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/95fae0db46a849ee85349e633d348698
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spelling	oai:doaj.org-article:95fae0db46a849ee85349e633d3486982021-12-02T17:01:46ZBacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification10.1038/s41467-019-09608-w2041-1723https://doaj.org/article/95fae0db46a849ee85349e633d3486982019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09608-whttps://doaj.org/toc/2041-1723Glycan molecules can be modified directly on the cell surface via chemoenzymatic approaches. Here, the authors employ a set of four bacterial glycosyltransferases to develop a live cell-based killing assay to probe host cell glycan-mediated influenza A virus infection.Senlian HongYujie ShiNicholas C. WuGeramie GrandeLacey DouthitHua WangWen ZhouK. Barry SharplessIan A. WilsonJia XiePeng WuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Senlian Hong Yujie Shi Nicholas C. Wu Geramie Grande Lacey Douthit Hua Wang Wen Zhou K. Barry Sharpless Ian A. Wilson Jia Xie Peng Wu Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
description	Glycan molecules can be modified directly on the cell surface via chemoenzymatic approaches. Here, the authors employ a set of four bacterial glycosyltransferases to develop a live cell-based killing assay to probe host cell glycan-mediated influenza A virus infection.
format	article
author	Senlian Hong Yujie Shi Nicholas C. Wu Geramie Grande Lacey Douthit Hua Wang Wen Zhou K. Barry Sharpless Ian A. Wilson Jia Xie Peng Wu
author_facet	Senlian Hong Yujie Shi Nicholas C. Wu Geramie Grande Lacey Douthit Hua Wang Wen Zhou K. Barry Sharpless Ian A. Wilson Jia Xie Peng Wu
author_sort	Senlian Hong
title	Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
title_short	Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
title_full	Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
title_fullStr	Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
title_full_unstemmed	Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
title_sort	bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/95fae0db46a849ee85349e633d348698
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Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

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