Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Developing an in vitro blood-brain-barrier (BBB) model that reproduces the organ’s complex structure and function is an open challenge. Here the authors present a BBB-on-a-chip that includes endothelial cells, pericytes and a 3D astrocytic network which resembles the morphology and function of astro...

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Bibliographic Details
Main Authors: Song Ih Ahn, Yoshitaka J. Sei, Hyun-Ji Park, Jinhwan Kim, Yujung Ryu, Jeongmoon J. Choi, Hak-Joon Sung, Tobey J. MacDonald, Allan I. Levey, YongTae Kim
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/95fd2b9d6594462fac69a3cba4e9f50b
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