An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.

The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored. Here, we report that the E3 ubiquitin ligase Cul7(Fbxw8) localizes to the Golgi c...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nadia Litterman, Yoshiho Ikeuchi, Gilbert Gallardo, Brenda C O'Connell, Mathew E Sowa, Steven P Gygi, J Wade Harper, Azad Bonni
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Acceso en línea:https://doaj.org/article/95fe3ac76055466ab7fac3447a55f84a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!